This monograph aims to make basic concepts in Enrique Dussel’s ethics of liberation more accessible to English language readers. Dussel’s infuence has been felt in the Global South for more than fve decades, but his voice is still not suffciently heard north of the Rio Grande. By reaching a broader audience, I seek to contribute to the dissemination of Dussel’s principled defense of human life and the biosphere at a time when both are threatened with catastrophe by the ravages of Western instrumental rationality.1 I intend, in particular, to articulate Dussel’s analectic method and show how the ethical principles developed in his magnum opus, Ethics of Liberation in the Age of Globalization and Exclusion (1998/2013), form the basis of norms in the economic and political felds. I argue that these norms provide a moral compass for those committed to transforming the prevailing system and advancing a planetary humanism.