, necroptosis, and pyroptosis are the three major ways of programed cell death (PCD) followingvirusinfection[1,2]. Amongthem,apoptosisisthemostextensivelyinvestigatedPCDduring viral infection. Apoptosis elicited by virus infection has both negative and positive influence on viral replication. Hostcellseliminatevirallyinfectedcellsviaapoptosis,whichabortsvirusinfection.